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Inhibition of Indoleamine 2,3 Dioxygenase Does Not Improve Cancer-Related Symptoms in a Murine Model of Human Papilloma Virus–Related Head and Neck Cancer

The expression of indoleamine 2,3 dioxygenase (IDO) by tumors can contribute to immunotolerance, and IDO induced by inflammation can also increase risk for the development of behavioral alterations. Thus, this study was initiated to determine whether IDO inhibition, intended to facilitate tumor clea...

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Detalles Bibliográficos
Autores principales: Vichaya, Elisabeth G, Vermeer, Daniel W, Budac, David, Lee, Anna, Grossberg, Aaron, Vermeer, Paola D, Lee, John H, Dantzer, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716175/
https://www.ncbi.nlm.nih.gov/pubmed/31496720
http://dx.doi.org/10.1177/1178646919872508