In Vivo and In Vitro Analyses of Novel Peptidomimetic Disruptors for the Serotonin 5-HT(2C) Receptor Interaction With Phosphatase and Tensin Homolog

Hypofunction of the serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) has been implicated in a variety of disorders including substance use disorders. As such, approaches to enhance 5-HT(2C)R signaling display therapeutic potential. In the present study, we show that disruption of the 5-HT(2C)R interac...

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Detalles Bibliográficos
Autores principales: Soto, Claudia A., Du, Huang-Chi, Fox, Robert G., Yang, Taegyun, Hooson, James, Anastasio, Noelle C., Gilbertson, Scott R., Cunningham, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716272/
https://www.ncbi.nlm.nih.gov/pubmed/31507411
http://dx.doi.org/10.3389/fphar.2019.00907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716272/
https://www.ncbi.nlm.nih.gov/pubmed/31507411
http://dx.doi.org/10.3389/fphar.2019.00907

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