RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration

RAD6 participates in DNA double-strand breaks (DSBs) repair by ubiquitinating histone H2B in mitotic cells. In terminally differentiated cells, however, the mechanisms of DNA damage repair are less well known. In this study, we investigate whether RAD6B is involved in DSBs repair in neurons and effe...

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Detalles Bibliográficos
Autores principales: Guo, Zhao, Tian, Yingxia, Guo, Yingli, Li, Boya, Liu, Xiangwen, Xie, Kun, Song, Yanfeng, Wang, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716356/
https://www.ncbi.nlm.nih.gov/pubmed/31507381
http://dx.doi.org/10.3389/fncel.2019.00392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716356/
https://www.ncbi.nlm.nih.gov/pubmed/31507381
http://dx.doi.org/10.3389/fncel.2019.00392

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