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RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration
RAD6 participates in DNA double-strand breaks (DSBs) repair by ubiquitinating histone H2B in mitotic cells. In terminally differentiated cells, however, the mechanisms of DNA damage repair are less well known. In this study, we investigate whether RAD6B is involved in DSBs repair in neurons and effe...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716356/ https://www.ncbi.nlm.nih.gov/pubmed/31507381 http://dx.doi.org/10.3389/fncel.2019.00392 |