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Phosphodiesterase 9A in Brain Regulates cGMP Signaling Independent of Nitric-Oxide
PDE9A is a cGMP-specific phosphodiesterase expressed in neurons throughout the brain that has attracted attention as a therapeutic target to treat cognitive disorders. Indeed, PDE9A inhibitors are under evaluation in clinical trials as a treatment for Alzheimer’s disease and schizophrenia. However,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716477/ https://www.ncbi.nlm.nih.gov/pubmed/31507355 http://dx.doi.org/10.3389/fnins.2019.00837 |