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Exogenous Let-7a-5p Induces A549 Lung Cancer Cell Death Through BCL2L1-Mediated PI3Kγ Signaling Pathway

Elevated expression of let-7a-5p contributes to suppression of lung cancer, in which let-7a-5p, as exosome cargo, can be transported from macrophages to lung cancer cells, yet the role of let-7a-5p remains unclear. Utilizing bioinformatics methods and cellular experiments, this study was designed an...

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Detalles Bibliográficos
Autores principales: Duan, Shuyin, Yu, Songcheng, Yuan, Teng, Yao, Sanqiao, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716507/
https://www.ncbi.nlm.nih.gov/pubmed/31508368
http://dx.doi.org/10.3389/fonc.2019.00808