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Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications

This article proposes the coupling of the recombinant protein avidin to the polysaccharide gellan gum to create a modular hydrogel substrate for 3D cell culture and tissue engineering. Avidin is capable of binding biotin, and thus biotinylated compounds can be tethered to the polymer network to impr...

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Detalles Bibliográficos
Autores principales: Gering, Christine, Koivisto, Janne T., Parraga, Jenny, Leppiniemi, Jenni, Vuornos, Kaisa, Hytönen, Vesa P., Miettinen, Susanna, Kellomäki, Minna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716642/
https://www.ncbi.nlm.nih.gov/pubmed/31469884
http://dx.doi.org/10.1371/journal.pone.0221931