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Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications
This article proposes the coupling of the recombinant protein avidin to the polysaccharide gellan gum to create a modular hydrogel substrate for 3D cell culture and tissue engineering. Avidin is capable of binding biotin, and thus biotinylated compounds can be tethered to the polymer network to impr...
Autores principales: | Gering, Christine, Koivisto, Janne T., Parraga, Jenny, Leppiniemi, Jenni, Vuornos, Kaisa, Hytönen, Vesa P., Miettinen, Susanna, Kellomäki, Minna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716642/ https://www.ncbi.nlm.nih.gov/pubmed/31469884 http://dx.doi.org/10.1371/journal.pone.0221931 |
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