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Chemokine signaling links cell-cycle progression and cilia formation for left–right symmetry breaking

Zebrafish dorsal forerunner cells (DFCs) undergo vigorous proliferation during epiboly and then exit the cell cycle to generate Kupffer’s vesicle (KV), a ciliated organ necessary for establishing left–right (L–R) asymmetry. DFC proliferation defects are often accompanied by impaired cilia elongation...

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Detalles Bibliográficos
Autores principales: Liu, Jingwen, Zhu, Chengke, Ning, Guozhu, Yang, Liping, Cao, Yu, Huang, Sizhou, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716676/
https://www.ncbi.nlm.nih.gov/pubmed/31430272
http://dx.doi.org/10.1371/journal.pbio.3000203