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Uncertainty reduction in biochemical kinetic models: Enforcing desired model properties
A persistent obstacle for constructing kinetic models of metabolism is uncertainty in the kinetic properties of enzymes. Currently, available methods for building kinetic models can cope indirectly with uncertainties by integrating data from different biological levels and origins into models. In th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716680/ https://www.ncbi.nlm.nih.gov/pubmed/31430276 http://dx.doi.org/10.1371/journal.pcbi.1007242 |