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Uncertainty reduction in biochemical kinetic models: Enforcing desired model properties

A persistent obstacle for constructing kinetic models of metabolism is uncertainty in the kinetic properties of enzymes. Currently, available methods for building kinetic models can cope indirectly with uncertainties by integrating data from different biological levels and origins into models. In th...

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Detalles Bibliográficos
Autores principales:	Miskovic, Ljubisa, Béal, Jonas, Moret, Michael, Hatzimanikatis, Vassily
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716680/ https://www.ncbi.nlm.nih.gov/pubmed/31430276 http://dx.doi.org/10.1371/journal.pcbi.1007242

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