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Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer

BACKGROUND: Colorectal Cancer (CRC) is a highly heterogeneous disease. RNA profiles of bulk tumors have enabled transcriptional classification of CRC. However, such ways of sequencing can only target a cell colony and obscure the signatures of distinct cell populations. Alternatively, single-cell RN...

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Detalles Bibliográficos
Autores principales: Dai, Weier, Zhou, Fangbin, Tang, Donge, Lin, Liewen, Zou, Chang, Tan, Wenyong, Dai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716720/
https://www.ncbi.nlm.nih.gov/pubmed/31441872
http://dx.doi.org/10.1097/MD.0000000000016916