Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson’s Disease

[Image: see text] Modulation of multiple biological targets with a single drug can lead to synergistic therapeutic effects and has been demonstrated to be essential for efficient treatment of CNS disorders. However, rational design of compounds that interact with several targets is very challenging....

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Detalles Bibliográficos
Autores principales: Jaiteh, Mariama, Zeifman, Alexey, Saarinen, Marcus, Svenningsson, Per, Bréa, Jose, Loza, Maria Isabel, Carlsson, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716773/
https://www.ncbi.nlm.nih.gov/pubmed/29792714
http://dx.doi.org/10.1021/acs.jmedchem.8b00204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716773/
https://www.ncbi.nlm.nih.gov/pubmed/29792714
http://dx.doi.org/10.1021/acs.jmedchem.8b00204

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