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Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson’s Disease
[Image: see text] Modulation of multiple biological targets with a single drug can lead to synergistic therapeutic effects and has been demonstrated to be essential for efficient treatment of CNS disorders. However, rational design of compounds that interact with several targets is very challenging....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716773/ https://www.ncbi.nlm.nih.gov/pubmed/29792714 http://dx.doi.org/10.1021/acs.jmedchem.8b00204 |