An automated high throughput solution for DNA extraction and bisulfite-conversion from high volume liquid biopsy specimens: sample preparation for epigenetic analysis

OBJECTIVE: DNA methylation analysis via real-time PCR or other analytical techniques requires purified bisulfite converted DNA. We report on an automated high throughput solution for DNA extraction, bisulfite-conversion, and purification of 96 samples with an input volume of up to 3.5 mL of plasma o...

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Detalles Bibliográficos
Autores principales: Rausch, Sebastian, Hasinger, Oliver, König, Thomas, Schlegel, Anne, Weiss, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716871/
https://www.ncbi.nlm.nih.gov/pubmed/31470896
http://dx.doi.org/10.1186/s13104-019-4595-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716871/
https://www.ncbi.nlm.nih.gov/pubmed/31470896
http://dx.doi.org/10.1186/s13104-019-4595-3

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