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Chrysosplenetin promotes osteoblastogenesis of bone marrow stromal cells via Wnt/β-catenin pathway and enhances osteogenesis in estrogen deficiency-induced bone loss

BACKGROUND: Chrysosplenetin is an O-methylated flavonol compound isolated from the plant Chamomilla recutita and Laggera pterodonta. The aim of our research is to evaluate the function of Chrysosplenetin on osteogenesis of human-derived bone marrow stromal cells (hBMSCs) and inhibition of estrogen d...

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Detalles Bibliográficos
Autores principales: Hong, Guoju, He, Xiaoming, Shen, Yingshan, Chen, Xiaojun, Yang, Fang, Yang, Peng, Pang, Fengxiang, Han, Xiaorui, He, Wei, Wei, Qiushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716882/
https://www.ncbi.nlm.nih.gov/pubmed/31464653
http://dx.doi.org/10.1186/s13287-019-1375-x