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Vaccination with viral vectors expressing NP, M1 and chimeric hemagglutinin induces broad protection against influenza virus challenge in mice

Seasonal influenza virus infections cause significant morbidity and mortality every year. Annual influenza virus vaccines are effective but only when well matched with circulating strains. Therefore, there is an urgent need for better vaccines that induce broad protection against drifted seasonal an...

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Detalles Bibliográficos
Autores principales: Asthagiri Arunkumar, Guha, McMahon, Meagan, Pavot, Vincent, Aramouni, Mario, Ioannou, Andriani, Lambe, Teresa, Gilbert, Sarah, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717082/
https://www.ncbi.nlm.nih.gov/pubmed/31399277
http://dx.doi.org/10.1016/j.vaccine.2019.07.095