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The interplay between intrinsic and extrinsic Wnt signaling in controlling intestinal transformation

The intestinal epithelial layer is the fastest renewing tissue in the human body. Due to its incredible turnover rate, the intestine is especially prone to develop cancer, in particular in the colon. Colorectal cancer (CRC) development is characterized by the stepwise accumulation of mutations over...

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Detalles Bibliográficos
Autores principales: van Neerven, Sanne M., Vermeulen, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717105/
https://www.ncbi.nlm.nih.gov/pubmed/30799131
http://dx.doi.org/10.1016/j.diff.2019.02.002