Broken force dispersal network in tip-links by the mutations at the Ca(2+)-binding residues induces hearing-loss

Tip-link as force-sensor in hearing conveys the mechanical force originating from sound to ion-channels while maintaining the integrity of the entire sensory assembly in the inner ear. This delicate balance between structure and function of tip-links is regulated by Ca(2+)-ions present in endolymph....

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Detalles Bibliográficos
Autores principales: Hazra, Jagadish P., Sagar, Amin, Arora, Nisha, Deb, Debadutta, Kaur, Simerpreet, Rakshit, Sabyasachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717114/
https://www.ncbi.nlm.nih.gov/pubmed/31399498
http://dx.doi.org/10.1042/BCJ20190453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717114/
https://www.ncbi.nlm.nih.gov/pubmed/31399498
http://dx.doi.org/10.1042/BCJ20190453

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