Synthesis of novel Schiff bases using 2-Amino-5-(3-fluoro-4-methoxyphenyl)thiophene-3-carbonitrile and 1,3-Disubstituted pyrazole-4-carboxaldehydes derivatives and their antimicrobial activity

2-Amino-5-(3-fluoro-4-methoxyphenyl)thiophene-3-carbonitrile have been synthesized from 1-(3-fluoro-4-methoxyphenyl)ethanone, malononitrile, a mild base and sulfur powder using Gewald synthesis technique and the intermediate was treated with 1,3-disubstituted pyrazole-4-carboxaldehyde to obtain the...

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Detalles Bibliográficos
Autores principales: Puthran, Divyaraj, Poojary, Boja, Purushotham, Nikil, Harikrishna, Nandam, Nayak, Soukhyarani Gopal, Kamat, Vinuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717141/
https://www.ncbi.nlm.nih.gov/pubmed/31485504
http://dx.doi.org/10.1016/j.heliyon.2019.e02233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717141/
https://www.ncbi.nlm.nih.gov/pubmed/31485504
http://dx.doi.org/10.1016/j.heliyon.2019.e02233

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