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Transcriptomic and functional analyses of 3D placental extravillous trophoblast spheroids

Placental extravillous trophoblast (EVT) invasion is essential in establishing proper blood supply to the fetus during pregnancy. However, traditional 2D in vitro systems do not model the in vivo invasion process in an anatomically-relevant manner. Our objectives were to develop a 3D spheroid model...

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Detalles Bibliográficos
Autores principales: Wong, Michael K., Wahed, Mishquatul, Shawky, Sarah A., Dvorkin-Gheva, Anna, Raha, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717201/
https://www.ncbi.nlm.nih.gov/pubmed/31471547
http://dx.doi.org/10.1038/s41598-019-48816-8