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Advanced Glycation End-Products Suppress Mitochondrial Function and Proliferative Capacity of Achilles Tendon-Derived Fibroblasts

Debilitating cases of tendon pain and degeneration affect the majority of diabetic individuals. The high rate of tendon degeneration persists even when glucose levels are well controlled, suggesting that other mechanisms may drive tendon degeneration in diabetic patients. The purpose of this study w...

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Detalles Bibliográficos
Autores principales: Patel, Shivam H., Yue, Feng, Saw, Shannon K., Foguth, Rachel, Cannon, Jason R., Shannahan, Jonathan H., Kuang, Shihuan, Sabbaghi, Arman, Carroll, Chad C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717202/
https://www.ncbi.nlm.nih.gov/pubmed/31471548
http://dx.doi.org/10.1038/s41598-019-49062-8