Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

Copy number alterations (CNAs) of 9p24.1 occur frequently in Hodgkin lymphoma, primary mediastinal large B-cell lymphoma (PMBCL), primary central nervous system lymphoma, and primary testicular lymphoma, resulting in overexpression of PD-L1 and sensitivity to PD-1 blockade-based immunotherapy. While...

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Detalles Bibliográficos
Autores principales: Wang, Yucai, Wenzl, Kerstin, Manske, Michelle K., Asmann, Yan W., Sarangi, Vivekananda, Greipp, Patricia T., Krull, Jordan E., Hartert, Keenan, He, Rong, Feldman, Andrew L., Maurer, Matthew J., Slager, Susan L., Nowakowski, Grzegorz S., Habermann, Thomas M., Witzig, Thomas E., Link, Brian K., Ansell, Stephen M., Cerhan, James R., Novak, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717207/
https://www.ncbi.nlm.nih.gov/pubmed/31471540
http://dx.doi.org/10.1038/s41408-019-0233-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717207/
https://www.ncbi.nlm.nih.gov/pubmed/31471540
http://dx.doi.org/10.1038/s41408-019-0233-5

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