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An in vitro model to explore subchondral perfusion and intraosseous pressure
BACKGROUND: Little is known about subchondral perfusion physiology. We developed a 3Rs (Replace, Reduce, Refine) compliant in vitro calf foot model to explore perfusion and intraosseous pressure (IOP). METHODS: Calf feet were catheterised and perfused with serum. IOP was measured at three sites, the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717224/ https://www.ncbi.nlm.nih.gov/pubmed/31471704 http://dx.doi.org/10.1186/s40634-019-0207-3 |