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The catalytic core of DEMETER guides active DNA demethylation in Arabidopsis

The Arabidopsis DEMETER (DME) DNA glycosylase demethylates the maternal genome in the central cell prior to fertilization and is essential for seed viability. DME preferentially targets small transposons that flank coding genes, influencing their expression and initiating plant gene imprinting. DME...

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Detalles Bibliográficos
Autores principales: Zhang, Changqing, Hung, Yu-Hung, Rim, Hyun Jung, Zhang, Dapeng, Frost, Jennifer M., Shin, Hosub, Jang, Hosung, Liu, Fang, Xiao, Wenyan, Iyer, Lakshminarayan M., Aravind, L., Zhang, Xiang-Qian, Fischer, Robert L., Huh, Jin Hoe, Hsieh, Tzung-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717269/
https://www.ncbi.nlm.nih.gov/pubmed/31409710
http://dx.doi.org/10.1073/pnas.1907290116