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An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

Dynamic small ubiquitin-like modifier (SUMO) linkages to diverse cellular protein groups are critical to orchestrate resolution of stresses such as genome damage, hypoxia, or proteotoxicity. Defense against pathogen insult (often reliant upon host recognition of “non-self” nucleic acids) is also mod...

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Detalles Bibliográficos
Autores principales: Schmidt, Nora, Domingues, Patricia, Golebiowski, Filip, Patzina, Corinna, Tatham, Michael H., Hay, Ronald T., Hale, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717285/
https://www.ncbi.nlm.nih.gov/pubmed/31391303
http://dx.doi.org/10.1073/pnas.1907031116