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An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity
Dynamic small ubiquitin-like modifier (SUMO) linkages to diverse cellular protein groups are critical to orchestrate resolution of stresses such as genome damage, hypoxia, or proteotoxicity. Defense against pathogen insult (often reliant upon host recognition of “non-self” nucleic acids) is also mod...
Autores principales: | Schmidt, Nora, Domingues, Patricia, Golebiowski, Filip, Patzina, Corinna, Tatham, Michael H., Hay, Ronald T., Hale, Benjamin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717285/ https://www.ncbi.nlm.nih.gov/pubmed/31391303 http://dx.doi.org/10.1073/pnas.1907031116 |
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