ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer

Although KRAS and TP53 mutations are major drivers of pancreatic ductal adenocarcinoma (PDAC), the incurable nature of this cancer still remains largely elusive. ARF6 and its effector AMAP1 are often overexpressed in different cancers and regulate the intracellular dynamics of integrins and E-cadher...

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Detalles Bibliográficos
Autores principales: Hashimoto, Shigeru, Furukawa, Shotaro, Hashimoto, Ari, Tsutaho, Akio, Fukao, Akira, Sakamura, Yurika, Parajuli, Gyanu, Onodera, Yasuhito, Otsuka, Yutaro, Handa, Haruka, Oikawa, Tsukasa, Hata, Soichiro, Nishikawa, Yoshihiro, Mizukami, Yusuke, Kodama, Yuzo, Murakami, Masaaki, Fujiwara, Toshinobu, Hirano, Satoshi, Sabe, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717289/
https://www.ncbi.nlm.nih.gov/pubmed/31399545
http://dx.doi.org/10.1073/pnas.1901765116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717289/
https://www.ncbi.nlm.nih.gov/pubmed/31399545
http://dx.doi.org/10.1073/pnas.1901765116

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