Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage

Trauma hemorrhage is a leading cause of death and disability worldwide. Platelets are fundamental to primary hemostasis, but become profoundly dysfunctional in critically injured patients by an unknown mechanism, contributing to an acute coagulopathy which exacerbates bleeding and increases mortalit...

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Detalles Bibliográficos
Autores principales: Vulliamy, Paul, Gillespie, Scarlett, Armstrong, Paul C., Allan, Harriet E., Warner, Timothy D., Brohi, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717295/
https://www.ncbi.nlm.nih.gov/pubmed/31405966
http://dx.doi.org/10.1073/pnas.1904978116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717295/
https://www.ncbi.nlm.nih.gov/pubmed/31405966
http://dx.doi.org/10.1073/pnas.1904978116

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