Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects

Hydrophobic base stacking is a major contributor to DNA double-helix stability. We report the discovery of specific unstacking effects in certain semihydrophobic environments. Water-miscible ethylene glycol ethers are found to modify structure, dynamics, and reactivity of DNA by mechanisms possibly...

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Detalles Bibliográficos
Autores principales: Feng, Bobo, Sosa, Robert P., Mårtensson, Anna K. F., Jiang, Kai, Tong, Alex, Dorfman, Kevin D., Takahashi, Masayuki, Lincoln, Per, Bustamante, Carlos J., Westerlund, Fredrik, Nordén, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717297/
https://www.ncbi.nlm.nih.gov/pubmed/31413203
http://dx.doi.org/10.1073/pnas.1909122116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717297/
https://www.ncbi.nlm.nih.gov/pubmed/31413203
http://dx.doi.org/10.1073/pnas.1909122116

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