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SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

BACKGROUND: Cancer genomes are peppered with somatic mutations imprinted by different mutational processes. The mutational pattern of a cancer genome can be used to identify and understand the etiology of the underlying mutational processes. A plethora of prior research has focused on examining muta...

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Detalles Bibliográficos
Autores principales: Bergstrom, Erik N., Huang, Mi Ni, Mahto, Uma, Barnes, Mark, Stratton, Michael R., Rozen, Steven G., Alexandrov, Ludmil B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717374/
https://www.ncbi.nlm.nih.gov/pubmed/31470794
http://dx.doi.org/10.1186/s12864-019-6041-2