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Raloxifene inhibits adipose tissue inflammation and adipogenesis through Wnt regulation in ovariectomized rats and 3 T3-L1 cells

BACKGROUND: Loss of ovarian function, as in menopause or after ovariectomy (OVX), is closely associated with obesity and white adipose tissue (WAT) inflammation. Estrogen replacement protects against postmenopausal obesity but increases the risks of carcinogenesis. In the present study, we investiga...

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Detalles Bibliográficos
Autores principales: Shen, Hsin-Hsueh, Yang, Chien-Yi, Kung, Ching-Wen, Chen, Shu-Ying, Wu, Hong-Min, Cheng, Pao-Yun, Lam, Kwok-Keung, Lee, Yen-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717377/
https://www.ncbi.nlm.nih.gov/pubmed/31470850
http://dx.doi.org/10.1186/s12929-019-0556-3