Anti-IL-13Rα2 therapy promotes recovery in a murine model of inflammatory bowel disease

There continues to be a major need for more effective inflammatory bowel disease (IBD) therapies. IL-13Rα2 is a decoy receptor that binds the cytokine IL-13 with high affinity and diminishes its STAT6-mediated effector functions. Previously, we found that IL-13Rα2 was necessary for IBD in mice defic...

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Detalles Bibliográficos
Autores principales: Karmele, E. P., Pasricha, T. S., Ramalingam, T. R., Thompson, R. W., Gieseck, R. L., Knilans, K. J., Hegen, M., Farmer, M., Jin, F., Kleinman, A., Hinds, D. A., Pereira, T. Almeida, de Queiroz Prado, R., Bing, N., Tchistiakova, L., Kasaian, M. T., Wynn, T. A., Vannella, K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717533/
https://www.ncbi.nlm.nih.gov/pubmed/31308480
http://dx.doi.org/10.1038/s41385-019-0189-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717533/
https://www.ncbi.nlm.nih.gov/pubmed/31308480
http://dx.doi.org/10.1038/s41385-019-0189-6

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