T-bet optimizes CD4 T-cell responses against influenza through CXCR3-dependent lung trafficking but not functional programming

Although clearance of many intracellular pathogens requires T-bet-dependent CD4 T cell programming, the extent to which T-bet is needed to direct protective CD4 responses against influenza is not known. Here, we characterize wild-type and T-bet-deficient CD4 cells during murine influenza infection....

Descripción completa

Detalles Bibliográficos
Autores principales: Dhume, Kunal, Finn, Caroline M., Strutt, Tara M., Sell, Stewart, McKinstry, K. Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717559/
https://www.ncbi.nlm.nih.gov/pubmed/31278374
http://dx.doi.org/10.1038/s41385-019-0183-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717559/
https://www.ncbi.nlm.nih.gov/pubmed/31278374
http://dx.doi.org/10.1038/s41385-019-0183-z

Ejemplares similares