Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis

Loss-of-function mutations in the ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane, ABCB7, cause X-linked sideroblastic anemia with ataxia, a phenotype that remains largely unexplained by the proposed role of ABCB7 in exporting a special sulfur species for use in cytosolic...

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Detalles Bibliográficos
Autores principales: Maio, Nunziata, Kim, Ki Soon, Holmes-Hampton, Gregory, Singh, Anamika, Rouault, Tracey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717564/
https://www.ncbi.nlm.nih.gov/pubmed/30765471
http://dx.doi.org/10.3324/haematol.2018.214320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717564/
https://www.ncbi.nlm.nih.gov/pubmed/30765471
http://dx.doi.org/10.3324/haematol.2018.214320

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