Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity

Chronic lymphocytic leukemia cells have an altered energy metabolism compared to normal B cells. While there is a growing understanding of the molecular heterogeneity of the disease, the extent of metabolic heterogeneity and its relation to molecular heterogeneity has not been systematically studied...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Junyan, Böttcher, Martin, Walther, Tatjana, Mougiakakos, Dimitrios, Zenz, Thorsten, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717593/
https://www.ncbi.nlm.nih.gov/pubmed/30792207
http://dx.doi.org/10.3324/haematol.2018.203067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717593/
https://www.ncbi.nlm.nih.gov/pubmed/30792207
http://dx.doi.org/10.3324/haematol.2018.203067

Ejemplares similares