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Targeting sickle cell disease root-cause pathophysiology with small molecules
The complex, frequently devastating, multi-organ pathophysiology of sickle cell disease has a single root cause: polymerization of deoxygenated sickle hemoglobin. A logical approach to disease modification is, therefore, to interdict this root cause. Ideally, such interdiction would utilize small mo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Ferrata Storti Foundation
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717594/ https://www.ncbi.nlm.nih.gov/pubmed/31399526 http://dx.doi.org/10.3324/haematol.2018.207530 |