New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia

Genetic iron-overload disorders, mainly hereditary hemochromatosis and untransfused β-thalassemia, affect a large population worldwide. The primary etiology of iron overload in these diseases is insufficient production of hepcidin by the liver, leading to excessive intestinal iron absorption and iro...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jing, Liu, Wei, Liu, Yin, Miao, Yang, Guo, Yifan, Song, Haoyang, Wang, Fudi, Zhou, Hongyu, Ganz, Tomas, Yan, Bing, Liu, Sijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717595/
https://www.ncbi.nlm.nih.gov/pubmed/30792208
http://dx.doi.org/10.3324/haematol.2018.209874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717595/
https://www.ncbi.nlm.nih.gov/pubmed/30792208
http://dx.doi.org/10.3324/haematol.2018.209874

Ejemplares similares