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New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia
Genetic iron-overload disorders, mainly hereditary hemochromatosis and untransfused β-thalassemia, affect a large population worldwide. The primary etiology of iron overload in these diseases is insufficient production of hepcidin by the liver, leading to excessive intestinal iron absorption and iro...
Autores principales: | Liu, Jing, Liu, Wei, Liu, Yin, Miao, Yang, Guo, Yifan, Song, Haoyang, Wang, Fudi, Zhou, Hongyu, Ganz, Tomas, Yan, Bing, Liu, Sijin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717595/ https://www.ncbi.nlm.nih.gov/pubmed/30792208 http://dx.doi.org/10.3324/haematol.2018.209874 |
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