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Lineage-dependent role of miR-410-3p as oncomiR in gonadotroph and corticotroph pituitary adenomas or tumor suppressor miR in somatotroph adenomas via MAPK, PTEN/AKT, and STAT3 signaling pathways

PURPOSE: miR-410-3p plays opposite roles in different cancers and may act as an oncomiR or tumor suppressor miR. The purpose of this study was to assess the role of miR-410-3p in somatotroph, gonadotroph, and corticotroph pituitary adenomas. METHODS: Tissue samples were obtained from 75 patients wit...

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Detalles Bibliográficos
Autores principales: Grzywa, Tomasz M., Klicka, Klaudia, Rak, Beata, Mehlich, Dawid, Garbicz, Filip, Zieliński, Grzegorz, Maksymowicz, Maria, Sajjad, Emir, Włodarski, Paweł K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717603/
https://www.ncbi.nlm.nih.gov/pubmed/31165412
http://dx.doi.org/10.1007/s12020-019-01960-7