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Onion peel extract and its constituent, quercetin inhibits human Slo3 in a pH and calcium dependent manner

Sperm function and male fertility are closely related to pH dependent K(+) current (KSper) in human sperm, which is most likely composed of Slo3 and its auxiliary subunit leucine-rich repeat-containing protein 52 (LRRC52). Onion peel extract (OPE) and its major active ingredient quercetin are widely...

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Detalles Bibliográficos
Autores principales: Wijerathne, Tharaka Darshana, Kim, Ji Hyun, Kim, Min Ji, Kim, Chul Young, Chae, Mee Ree, Lee, Sung Won, Lee, Kyu Pil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717788/
https://www.ncbi.nlm.nih.gov/pubmed/31496875
http://dx.doi.org/10.4196/kjpp.2019.23.5.381