Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation

PURPOSE: Polyphyllin VI, a main active saponin isolated from traditional medicinal plant Paris polyphylla, has exhibited antitumor activities in several cancer cell lines. In the present study, we investigated the antitumor effect of Polyphyllin VI against human osteosarcoma cells (U2OS) and the und...

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Detalles Bibliográficos
Autores principales: Yuan, Yong-Liang, Jiang, Neng, Li, Ze-Yun, Song, Zhi-Zhen, Yang, Zhi-Heng, Xue, Wen-Hua, Zhang, Xiao-Jian, Du, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717844/
https://www.ncbi.nlm.nih.gov/pubmed/31695327
http://dx.doi.org/10.2147/DDDT.S194961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717844/
https://www.ncbi.nlm.nih.gov/pubmed/31695327
http://dx.doi.org/10.2147/DDDT.S194961

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