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The effect of A1 adenosine receptor in diabetic megalin loss with caspase-1/IL18 signaling

PURPOSE: In our previous study, exacerbation of albuminuria was observed in A1 adenosine receptor knockout (A1AR(−/-)) mice with diabetic nephropathy (DN), but the mechanism was unclear. Here, we investigated the relationship of megalin loss and albuminuria, to identify the protective effect of A1AR...

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Detalles Bibliográficos
Autores principales: Tian, Dongli, Shi, Xiaoxiao, Zhao, Yumo, Peng, Xiaoyan, Zou, Linfeng, Xu, Lubin, Ma, Ying, Wen, Yubin, Faulhaber-Walter, Robert, Chen, Limeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717852/
https://www.ncbi.nlm.nih.gov/pubmed/31695457
http://dx.doi.org/10.2147/DMSO.S215531