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Targeting breast cancer stem cells by a self-assembled, aptamer-conjugated DNA nanotrain with preloading doxorubicin

BACKGROUND: Cancer relapse and metastasis is an obstacle to the treatment of breast cancer. Breast cancer stem cells (BCSCs), which can evade the killing effect of traditional chemotherapies, such as doxorubicin (DOX), may contribute to cancer development. Therefore, it is necessary to develop novel...

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Detalles Bibliográficos
Autores principales: Xu, Zhiyuan, Ni, Ronghua, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717853/
https://www.ncbi.nlm.nih.gov/pubmed/31695364
http://dx.doi.org/10.2147/IJN.S200482