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Aβ43 in human Alzheimer’s disease: effects of active Aβ42 immunization

Neuropathological follow-up of patients with Alzheimer’s disease (AD) who participated in the first clinical trial of Amyloid-β 42 (Aβ42) immunization (AN1792, Elan Pharmaceuticals) has shown that immunization can induce removal of Aβ42 and Aβ40 from plaques, whereas analysis of the cerebral vessels...

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Detalles Bibliográficos
Autores principales: Jäkel, Lieke, Boche, Delphine, Nicoll, James A. R., Verbeek, Marcel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717966/
https://www.ncbi.nlm.nih.gov/pubmed/31477180
http://dx.doi.org/10.1186/s40478-019-0791-6