MPRAnalyze: statistical framework for massively parallel reporter assays

Massively parallel reporter assays (MPRAs) can measure the regulatory function of thousands of DNA sequences in a single experiment. Despite growing popularity, MPRA studies are limited by a lack of a unified framework for analyzing the resulting data. Here we present MPRAnalyze: a statistical frame...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashuach, Tal, Fischer, David S., Kreimer, Anat, Ahituv, Nadav, Theis, Fabian J., Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717970/
https://www.ncbi.nlm.nih.gov/pubmed/31477158
http://dx.doi.org/10.1186/s13059-019-1787-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717970/
https://www.ncbi.nlm.nih.gov/pubmed/31477158
http://dx.doi.org/10.1186/s13059-019-1787-z

Ejemplares similares