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Growth arrest-specific gene 2 suppresses hepatocarcinogenesis by intervention of cell cycle and p53-dependent apoptosis

BACKGROUND: Growth arrest-specific gene 2 (GAS2) plays a role in modulating in reversible growth arrest cell cycle, apoptosis, and cell survival. GAS2 protein is universally expressed in most normal tissues, particularly in the liver, but is depleted in some tumor tissues. However, the functional me...

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Detalles Bibliográficos
Autores principales: Zhu, Ran-Xu, Cheng, Alfred Sze Lok, Chan, Henry Lik Yuen, Yang, Dong-Ye, Seto, Wai-Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718038/
https://www.ncbi.nlm.nih.gov/pubmed/31528096
http://dx.doi.org/10.3748/wjg.v25.i32.4715