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Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression

The protein α-synuclein (αsyn) forms pathologic aggregates in a number of neurodegenerative diseases including Lewy body dementia (LBD) and Parkinson’s disease (PD). It is unclear why diseases such as LBD may develop widespread αsyn pathology, while in Alzheimer’s disease with amygdala restricted Le...

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Detalles Bibliográficos
Autores principales: Sorrentino, Zachary A., Goodwin, Marshall S., Riffe, Cara J., Dhillon, Jess-Karan S., Xia, Yuxing, Gorion, Kimberly-Marie, Vijayaraghavan, Niran, McFarland, Karen N., Golbe, Lawrence I., Yachnis, Anthony T., Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718048/
https://www.ncbi.nlm.nih.gov/pubmed/31477175
http://dx.doi.org/10.1186/s40478-019-0787-2