Structure of GTP cyclohydrolase I from Listeria monocytogenes, a potential anti-infective drug target

A putative open reading frame encoding GTP cyclohydrolase I from Listeria monocytogenes was expressed in a recombinant Escherichia coli strain. The recombinant protein was purified and was confirmed to convert GTP to dihydroneopterin triphosphate (K (m) = 53 µM; v (max) = 180 nmol mg(−1) min(−1)). T...

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Detalles Bibliográficos
Autores principales: Schüssler, Sonja, Haase, Ilka, Perbandt, Markus, Illarionov, Boris, Siemens, Alexandra, Richter, Klaus, Bacher, Adelbert, Fischer, Markus, Gräwert, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718149/
https://www.ncbi.nlm.nih.gov/pubmed/31475925
http://dx.doi.org/10.1107/S2053230X19010902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718149/
https://www.ncbi.nlm.nih.gov/pubmed/31475925
http://dx.doi.org/10.1107/S2053230X19010902

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