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The adipokinetic hormones and their cognate receptor from the desert locust, Schistocerca gregaria: solution structure of endogenous peptides and models of their binding to the receptor

BACKGROUND: Neuropeptides exert their activity through binding to G protein-coupled receptors (GPCRs). GPCRs are well-known drug targets in the pharmaceutical industry and are currently discussed as targets to control pest insects. Here, we investigate the neuropeptide adipokinetic hormone (AKH) sys...

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Detalles Bibliográficos
Autores principales: Jackson, Graham E., Pavadai, Elumalai, Gäde, Gerd, Andersen, Niels H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718158/
https://www.ncbi.nlm.nih.gov/pubmed/31531269
http://dx.doi.org/10.7717/peerj.7514